Thermo Fisher Scientific CRP Polyclonal Antibody

Applications

• Western Blot (WB)
  Tested Dilution: 1:10,000
  View 1 publication

Product Specifications

Product Specific Information

Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
After reconstitution, keep aliquots at -20°C for higher stability, and at 4°C with an appropriate antibacterial agent.

Target Information

CRP (C-reactive protein) is a major cyclic, pentameric acute phase protein composed of five identical, noncovalently bound, nonglycosylated subunits. Each subunit consists of 206 amino acids with a molecular weight of 24 kDa.
CRP is produced by the liver and its plasma levels rise dramatically during inflammatory processes. It initiates the classical complement cascade, binds to nuclear components (chromatin, histones), and plays a crucial role in innate immunity.
CRP acts as an opsonin, activates monocytes/macrophages, and functions as a scavenger during cell necrosis. Elevated CRP levels are associated with increased risk of hypertension and cardiovascular disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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