Thermo Fisher Scientific ICAM3 Monoclonal Antibody (OTI3A7), TrueMAB
인간 ICAM3 단백질을 인식하는 단클론 항체로, Western blot에 최적화되어 있습니다. Mouse IgG2b 형식의 TrueMAB 제품으로, 높은 특이성과 재현성을 제공합니다. 액상 형태로 1 mg/mL 농도이며, PBS/BSA/glycerol 버퍼에 보존되어 있습니다.
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Applications
- Western Blot (WB)
Tested Dilution
- 1:400–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3A7 |
| Immunogen | Full length human recombinant protein of human ICAM3 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD50 (intracellular adhesion molecule 3, ICAM-3) is a transmembrane glycoprotein expressed by leukocytes that serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin.
ICAM-3 mediates contact between T cells and antigen-presenting cells, regulates LFA-1 affinity for ICAM-1, and induces T cell activation and proliferation.
It plays an essential role in initiating immune responses and interacts with CD209 (DC-SIGN), facilitating communication between dendritic cells and granulocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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