Thermo Fisher Scientific CD3/CD45RA Antibody Cocktail, FITC, PE

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

Neat

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Miscellaneous PubMed (Misc)

-

View 4 publications 4 publications

Product Specifications

Published species

Rat

Host/Isotype

Mouse / IgG1/IgM

Class

Cocktail

Type

Antibody

Clone

IF4/OX-33

Immunogen

Purified rat LCA

Conjugate

FITC , PE FITC , PE FITC , PE

Form

Lyophilized

Concentration

Conc. Not Determined

Storage conditions

4° C, store in dark, DO NOT FREEZE!

Shipping conditions

Wet ice

RRID

AB_2538218

Product Specific Information

MA5-16726 contains a monoclonal mixture of FITC-conjugated CD3 (clone #IF4, Mouse IgM) and RPE-conjugated CD45RA (clone #OX-33, Mouse IgG1). This antibody is a dual-color reagent recognizing rat CD3 and CD45RA cell surface antigens. Clone IF4 recognizes rat CD3, a cell surface antigen expressed by mature lymphocytes. Clone OX-33 recognizes rat CD45RA, a cell surface antigen expressed by B-lymphocytes.

Reconstitute with 1 mL of distilled water. After reconstitution, store product undiluted at 4ºC in the dark.

For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.

Target Information

CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.