Thermo Fisher Scientific AHA1 Polyclonal Antibody
Thermo Fisher Scientific의 AHA1 Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하며 WB, IHC, ICC/IF, ELISA, IP 등 다양한 응용 가능. Rabbit IgG 폴리클로날 항체로 Protein A로 정제됨. HSP90AA1의 코샤페론으로 연구용에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1:60 |
| Immunocytochemistry (ICC/IF) | 1:200 |
| ELISA | Assay-Dependent |
| Immunoprecipitation (IP) | Assay-Dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full-length mouse Aha1 (UniProt ID: Q8BK64-1, Antigen Range: 1–338) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2735436 |
Product Specific Information
1 µL/mL of PA5-77804 was sufficient for detection of Aha1 in 10 µg of mixed human cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Detects approximately 38 kDa.
Target Information
Acts as a co-chaperone of HSP90AA1 (PubMed:29127155). Activates the ATPase activity of HSP90AA1 leading to increased chaperone activity (PubMed:29127155).
Competes with inhibitory co-chaperones FNIP1 and TSC1 for binding to HSP90AA1, providing reciprocal regulatory mechanisms for chaperoning of client proteins (PubMed:27353360, 29127155).
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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