Thermo Fisher Scientific MMP-17 (MT4-MMP, MT-MMP-4) Polyclonal Antibody
MMP-17(MT4-MMP) 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot 및 IHC에 적합하며 Human, Mouse, Rat 반응성을 보입니다. 항원 친화 크로마토그래피로 정제되었으며 장기 보관 시 -20°C에서 안정적입니다.
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Thermo Fisher Scientific MMP-17 (MT4-MMP, MT-MMP-4) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to internal segment of human MMP-17 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Small intestine
- Cellular location: Extracellular matrix
Target Information
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes like arthritis and metastasis.
Most MMPs are secreted as inactive proproteins that are activated when cleaved by extracellular proteinases.
The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, it is unique among MT-MMPs in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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