Thermo Fisher Scientific IL-3 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Target Information

Interleukin 3 (IL-3), also known as Mast Cell Growth Factor (MCGF), Multi-Colony Stimulating Factor (multi-CSF), or Eosinophil-CSF (E-CSF), is produced by activated T cells, mast cells, and eosinophils.
IL-3 is a hematopoietic growth factor that stimulates colony formation of erythroid, megakaryocyte, neutrophil, eosinophil, basophil, mast cell, and monocytic lineages.
These functions are often enhanced or dependent on co-stimulation with other cytokines.

Human and mouse IL-3 share only 29% sequence identity at the amino acid level, and IL-3 bioactivity is highly species-specific — for example, human IL-3 shows no activity on mouse cells.
IL-3 supports the proliferation of a broad range of hematopoietic cell types and is involved in cell growth, differentiation, and apoptosis. It also possesses neurotrophic activity and may be associated with neurologic disorders.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.