Thermo Fisher Scientific DECR2 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

ELISA

• Tested Dilution: 1 µg/mL

Product Specifications

Product Specific Information

• Positive test controls: HeLa, Mouse liver, Rat liver, Rat kidney
• Immunogen sequence:
  GTFNVSRVLY EKFFRDHGGV IVNITATLGN RGQALQVHAG SAKAAVDAMT RHLAVEWGPQ NIRVNSLAPG PISGTEGLRR LGGPQASLST KVTASPLQRL G

Target Information

DECR2 (2,4-dienoyl-CoA reductase 2), also known as PDCR (peroxisomal 2,4-dienoyl-CoA reductase) or SDR17C1, is a 292 amino acid member of the short-chain dehydrogenases/reductases (SDR) family and the 2,4-dienoyl-CoA reductase subfamily.
Localized to the peroxisome, DECR2 catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to trans-3-enoyl-CoA.
It also shows activity toward 2,4,7,10,13,16,19-docosaheptaenoyl-CoA and short/medium chain 2,4-dienoyl-CoAs, indicating DECR2 is not rate-limiting in docosahexaenoic acid degradation.
DECR2 is expressed as three isoforms produced by alternative splicing.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.