Thermo Fisher Scientific DECR2 Polyclonal Antibody
Thermo Fisher Scientific의 DECR2 Polyclonal Antibody는 인간, 마우스, 랫트 반응성을 가진 rabbit IgG 항체로, Western blot 및 ELISA에 적합합니다. DECR2 단백질의 140-240 아미노산 서열을 기반으로 제작되었으며, 액상 형태로 -20°C 보관이 권장됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 140–240 of human DECR2 (NP_065715.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.48 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914143 |
Product Specific Information
- Positive test controls: HeLa, Mouse liver, Rat liver, Rat kidney
- Immunogen sequence:
GTFNVSRVLY EKFFRDHGGV IVNITATLGN RGQALQVHAG SAKAAVDAMT RHLAVEWGPQ NIRVNSLAPG PISGTEGLRR LGGPQASLST KVTASPLQRL G
Target Information
DECR2 (2,4-dienoyl-CoA reductase 2), also known as PDCR (peroxisomal 2,4-dienoyl-CoA reductase) or SDR17C1, is a 292 amino acid member of the short-chain dehydrogenases/reductases (SDR) family and the 2,4-dienoyl-CoA reductase subfamily.
Localized to the peroxisome, DECR2 catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to trans-3-enoyl-CoA.
It also shows activity toward 2,4,7,10,13,16,19-docosaheptaenoyl-CoA and short/medium chain 2,4-dienoyl-CoAs, indicating DECR2 is not rate-limiting in docosahexaenoic acid degradation.
DECR2 is expressed as three isoforms produced by alternative splicing.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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