Thermo Fisher Scientific Caspase 6 (Cleaved Asp179) Polyclonal Antibody
Caspase 6 단백질의 활성화 절편(Asp179 인접 절단 부위)을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 적합합니다. 인간 및 랫트 반응성, 고순도 Affinity 정제, -20°C 보관, 연구용 전용 제품입니다.
- 카탈로그번호
- PA599464
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- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Caspase 6 (Cleaved Asp179) Polyclonal Antibody
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CASP6 (Accession P55212), corresponding to amino acid residues C163–I189 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS (pH 7.4) with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818397 |
Product Specific Information
This antibody detects endogenous levels of the fragment of activated Caspase 6 resulting from cleavage adjacent to Asp179.
Target Information
Caspases are cysteine proteases expressed as inactive precursors that mediate apoptosis by proteolysis of specific substrates. They cleave after aspartic acid residues and are divided into initiator and effector classes. Initiator caspases (e.g., Caspase-8, Caspase-9) activate effector caspases (e.g., Caspase-3, Caspase-7), leading to cellular apoptosis and collapse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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