Thermo Fisher Scientific ZBTB17 Monoclonal Antibody (OTI2G1), TrueMAB
ZBTB17 단백질을 인식하는 Monoclonal Antibody로 Western Blot에 최적화됨. Human, Mouse, Rat 반응성. Lyophilized 형태로 제공되며, PBS buffer에 trehalose 포함. 세포 발달 및 전사 조절 연구에 적합.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2G1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 112–457 of human ZBTB17 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
ZBTB17 is a transcription factor that can act as an activator or repressor depending on binding partners. It targets negative regulators of cell cycle progression and plays a critical role in early lymphocyte development by preventing apoptosis in lymphoid precursors, supporting survival in response to IL7 and proper lineage commitment. It binds to promoters of adenovirus major late protein and cyclin D1 to activate transcription and is required for early embryonic development during gastrulation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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