Thermo Fisher Scientific ZBTB17 Monoclonal Antibody (OTI7D8), TrueMAB
ZBTB17 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI7D8). Western blot에 최적화되어 있으며 Human, Mouse, Rat 시료에 반응. 동결건조 형태로 제공되며 PBS buffer에 8% trehalose 포함. 연구용으로 세포 발달 및 전사 조절 연구에 적합.
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7D8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 112–457 of human ZBTB17 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
ZBTB17 is a transcription factor that can act as both an activator and repressor depending on its binding partners. It regulates negative modulators of cell cycle progression and is critical for early lymphocyte development by preventing apoptosis in lymphoid precursors, enabling IL7 responsiveness and lineage commitment.
It binds promoters of adenovirus major late protein and cyclin D1 to activate transcription and is required for early embryonic development during gastrulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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