Thermo Fisher Scientific Cytokeratin 16 (KRT16) Recombinant Mouse Monoclonal Antibody (rKRT16, 1714)
인간 Cytokeratin 16을 인식하는 재조합 마우스 단클론 항체로, IHC(P) 실험에 적합합니다. HEK293 세포에서 발현되었으며, Protein A/G로 정제되었습니다. 보존제가 없는 액상 형태이며, -20°C 이하에서 보관 가능합니다. 연구용으로만 사용됩니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | rKRT16, 1714 |
| Immunogen | Recombinant fragment from the C-terminal of human Cytokeratin 16 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
KRT16 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most type I cytokeratins consist of acidic proteins arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12–q21.
This keratin is coexpressed with keratin 14 in several epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma, and unilateral palmoplantar verrucous nevus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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