Thermo Fisher Scientific BAMBI Polyclonal Antibody
BAMBI 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 ELISA에 적합하며, 인간 및 랫트 시료에 반응. 고순도 친화 크로마토그래피 정제, 액상 형태로 안정적 보관 가능.
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Thermo Fisher Scientific BAMBI Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 21–152 of human BAMBI (NP_0364741) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.19 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806598 |
Product Specific Information
- Immunogen sequence:
VLLTKGEIRC YCDAAHCVAT GYMCKSELSA CFSRLLDPQN SNSPLTHGCL DSLASTTDIC QAKQARNHSG TTIPTLECCH EDMCNYRGLH DVLSPPRGEA SGQGNRYQHD GSRNLITKVQ ELTSSKELWF RA - Positive Samples: A-549, Rat heart
- Cellular Location: Membrane, Single-pass type I membrane protein
Target Information
BAMBI (BMP and activin membrane-bound inhibitor homolog, NMA) is a membrane-spanning glycoprotein that acts as a negative regulator of TGF-beta signaling during development. BAMBI transcription is regulated by beta-catenin, BMP, smad3, and smad4. Its expression increases in colorectal and hepatocellular carcinomas relative to non-cancerous tissues and is highly expressed during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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