Thermo Fisher Scientific PPP1R8 Polyclonal Antibody
Human PPP1R8 단백질에 특이적인 Rabbit Polyclonal 항체로, WB 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS(40% glycerol) 용액 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PPP1R8. Recombinant protein control fragment (Product #RP-94132). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.08 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645882 |
Product Specific Information
Immunogen sequence:
TFLGHIRLEP HKPQQIPIDS TVSFGASTRA YTLREKPQTL PSAVKGDEKM GGEDDELKGL LGLPEEETEL DNLTEFNTAH NK
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 100%
Target Information
This gene, through alternative splicing, encodes three different isoforms.
Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA.
The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli.
This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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