Thermo Fisher Scientific STK36 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human STK36. Recombinant protein control fragment (Product #RP-95073). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:STK36,uniProtId:Q9NRP7-1,ncbiNodeId:9606,antigenRange:876-957,antigenLength:1315,antigenImageFileName:PA5-55625_STK36_Q9NRP7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-55625_STK36_Q9NRP7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2648022

Product Specific Information

Immunogen sequence: EMWTVLWHRF SMVLRLPEEA SAQEGELSLS SPPSPEPDWT LISPQGMAAL LSLAMATFTQ EPQLCLSCLS QHGSILMSIL KH

Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 84%.

Target Information

Serine/threonine protein kinase required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.