Thermo Fisher Scientific STK36 Polyclonal Antibody
Human STK36 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS(40% glycerol) 완충액에 보관됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA555625
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human STK36. Recombinant protein control fragment (Product # RP-95073) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2648022 |
Product Specific Information
Immunogen sequence:
EMWTVLWHRF SMVLRLPEEA SAQEGELSLS SPPSPEPDWT LISPQGMAAL LSLAMATFTQ EPQLCLSCLS QHGSILMSIL KH
Sequence identity:
Highest antigen sequence identity to the following orthologs:
- Mouse: 82%
- Rat: 84%
Target Information
Serine/threonine protein kinase required for postnatal development, possibly by regulating the homeostasis of cerebrospinal fluid or ciliary function. Controls the activity of the transcriptional regulators GLI1, GLI2, and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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