Thermo Fisher Scientific Bmf Polyclonal Antibody
Bmf 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. 세포사멸 관련 연구용으로 적합하며, 인간 시료에 반응.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Bmf. Recombinant protein control fragment (Product #RP-88647) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856170 |
Product Specific Information
Immunogen sequence:
VEELEDDVFQ PEDGEPVTQP GSLLSADLFA QSLLDCPLSR LQLFPLTHCC GPGLRPTSQE DKATQTLSPA SPSQGVMLPC GVTEEPQRLF YGNAGYRLPL PASFPAVLPI GEQPPEGQWQ HQAEVQIARK LQCIADQFHR LHVQQHQQNQ
Target Information
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators involved in various cellular activities.
This protein contains a single BCL2 homology domain 3 (BH3) and functions as an apoptotic activator by binding BCL2 proteins.
It is sequestered to myosin V motors via association with dynein light chain 2, which may play a role in sensing intracellular damage and triggering apoptosis.
Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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