Thermo Fisher Scientific TEM8 Polyclonal Antibody
TEM8 단백질을 검출하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 IHC(Paraffin)에서 검증됨. 인간 및 마우스 시료 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체. 암 관련 연구 및 Bacillus anthracis 수용체 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic Peptide: L(92) M K L T E D R E Q I R Q G L E(107) C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with 1mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2056888 |
Product Specific Information
PA1-602 detects Tem-8 from mouse samples.
PA1-602 has been successfully used in Western blot and immunohistochemical procedures.
By Western blot, this antibody detects ~45 kDa, 60 kDa, and 85 kDa proteins representing Tem-8 from mouse tissue extracts.
This antibody has also been used in immunohistochemical procedures (paraffin samples) using mouse tissues.
PA1-602 immunizing peptide corresponds to amino acid residues 92–107 within the extracellular domain of human ATR/TEM8.
This peptide (Cat. # PEP-253) is available for neutralization and control experiments.
Target Information
This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker implicated in colorectal cancer.
The encoded protein also acts as a docking receptor for Bacillus anthracis toxin, mediating delivery of toxin components to the cytosol.
Once inside the cell, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.
Three alternatively spliced variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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