Thermo Fisher Scientific TNK1 Monoclonal Antibody (E.359.10)
TNK1 단백질을 표적하는 Rabbit IgG 단클론 항체로, Western blot에 최적화되어 있습니다. 고순도 친화 크로마토그래피 정제, 액상 형태, 높은 농도(27.4 mg/mL)로 제공됩니다. TNK1 신호전달 및 종양 억제 연구용으로 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | E.359.10 |
| Immunogen | Synthetic peptide corresponding to the sequence around Pro97 of human TNK1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 27.4 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10985367 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with other related proteins.
Target Information
TNK1 tyrosine kinase, non-receptor 1 belongs to the tyrosine protein kinase family and is an important regulator of intracellular signal transduction pathways mediating cellular proliferation, survival, and development. TNK1 is highly expressed in fetal tissues and at lower levels in a few adult tissues. It may function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues. TNK1 plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: MA5-14860_TNK1_Q13470-1_Rabbit.svg)
(이미지: MA5-14860_TNK1_Q13470-1_Rabbit_PDP.jpeg)
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