Thermo Fisher Scientific ZFP36 Monoclonal Antibody (OTI4B10), TrueMAB
ZFP36 단백질을 인식하는 Mouse 모노클로날 항체로, Western blot 및 Flow cytometry에 적합합니다. Lyophilized 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능합니다. 성장 인자 반응 조절과 염증 관련 연구에 유용합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4B10 |
| Immunogen | Full length human recombinant protein of human ZFP36 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
ZFP36 is a regulatory protein with a zinc finger structure involved in the cellular response to growth factors.
Knockdown of ZFP36 increases macrophage gene mRNAs and inflammatory TNF protein release, while overexpression decreases these levels, indicating its role in macrophage gene regulation.
ZFP36 can be phosphorylated by JNK and other MAP kinases. Its expression levels have been linked to prostate cancer outcomes and rheumatoid arthritis disease activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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