Thermo Fisher Scientific BTLA Polyclonal Antibody
BTLA 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Mouse 반응성, Goat 유래 IgG 포맷으로 Western blot에 적합. 인간 및 rat에서도 예측 반응성. 액상 형태, 0.5 mg/mL 농도, 연구용 전용.
- 카탈로그번호
- PA519048
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host/Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (KEAPTEYASICVRS) corresponding to the C-terminus amino acids of BTLA (aa 297–306) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_10983094 |
Product Specific Information
- This antibody is predicted to react with human and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:4000.
Target Information
BTLA (B and T-lymphocyte attenuator) is a member of the co-inhibitory receptors of the CD28 superfamily.
It functions as a lymphocyte inhibitory receptor that suppresses lymphocyte activation during immune responses.
BTLA is constitutively expressed on most CD4+ and CD8+ T cells, with expression decreasing upon activation.
It remains expressed on Th1 cells but not Th2 cells.
BTLA interacts with herpesvirus entry mediator (HVEM), a TNF receptor superfamily member, forming an important regulatory pathway for lymphocyte activation and immune homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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