Thermo Fisher Scientific BTLA Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1-3 µg/mL

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide sequence (KEAPTEYASICVRS) corresponding to the C-terminus amino acids of BTLA (aa 297-306). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:BTLA (CD272),uniProtId:Q7TSA3-1,ncbiNodeId:10090,antigenRange:297-306,antigenLength:306,antigenImageFileName:PA5-19048_BTLA_CD272_Q7TSA3-1_Goat.svg,antigenImageFileNamePDP:PA5-19048_BTLA_CD272_Q7TSA3-1_Goat_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Ammonium sulfate precipitation

Storage buffer

TBS, pH 7.3, with 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_10983094

Product Specific Information

This antibody is predicted to react with human and rat based on sequence homology.

This antibody is tested in Peptide ELISA: antibody detection limit dilution 4,000.

Target Information

BTLA or B and T-lymphocyte attenuator is a member of the co-inhibitory receptors of the CD28 superfamily. BTLA is a lymphocyte inhibitory receptor which inhibits lymphocytes during immunes responses. BTLA is constitutively expressed on most CD4+ and CD8+ T cells and its expression progressively decreases upon T cell activation. It remains expressed on Th1 cells, but not Th2 cells. BTLA is a unique co-receptor that interacts with the tumor necrosis factor receptor superfamily member herpesvirus entry mediator (HVEM). This interation is an important pathway regulating lymphocyte activation and/or homeostasis in the immune response.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.