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Thermo Fisher Scientific PNMA2 Monoclonal Antibody (4F10)
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Thermo Fisher Scientific PNMA2 Monoclonal Antibody (4F10)

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PNMA2 단백질을 표적하는 Thermo Fisher Scientific의 단클론 항체(4F10)로, 인간 시료에 반응하며 WB, ICC/IF, ELISA, IP 등 다양한 실험에 사용 가능. 고순도 친화 크로마토그래피 정제, PBS 저장용액, 무보존제, 연구용 전용.

카탈로그번호
H00010687-M10
판매단위
pk
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마지막 업데이트 2025. 08. 04. 오후 02:07
Thermo Fisher Scientific H00010687-M10 PNMA2 Monoclonal Antibody (4F10) 100 ug pk판매 단위 pk ·
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Thermo Fisher Scientific · Thermo Fisher Scientific PNMA2 Monoclonal Antibody (4F10)

Thermo Fisher Scientific PNMA2 Monoclonal Antibody (4F10)

Applications and Tested Dilutions

Application Tested Dilution
Western Blot (WB) 1–5 µg/mL
Immunocytochemistry (ICC/IF) 10 µg/mL
ELISA 3 ng/mL
Immunoprecipitation (IP) 1–5 µg/mL

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Mouse / IgG2a, kappa
Class Monoclonal
Type Antibody
Clone 4F10
Immunogen PNMA2 (AAH62301, 1–364 a.a) full-length recombinant protein with GST tag (MW of GST tag: 26 kDa)
Conjugate Unconjugated
Form Liquid
Concentration See Label
Purification Affinity chromatography
Storage Buffer PBS, pH 7.4
Contains No preservative
Storage Conditions -20°C, Avoid Freeze/Thaw Cycles
Shipping Conditions Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of PNMA2 protein:

MALALLEDWC RIMSVDEQKS LMVTGIPADF EEAEIQEVLQ ETLKSLGRYR LLGKIFRKQE NANAVLLELL EDTDVSAIPS EVQGKGGVWK VIFKTPNQDT EFLERLNLFL EKEGQTVSGM FRALGQEGVS PATVPCISPE LLAHLLGQAM AHAPQPLLPM RYRKLRVFSG SAVPAPEEES FEVWLEQATE IVKEWPVTEA EKKRWLAESL RGPALDLMHI VQADNPSISV EECLEAFKQV FGSLESRRTA QVRYLKTYQE EGEKVSAYVL RLETLLRRAV EKRAIPRRIA DQVRLEQVMA GATLNQMLWC RLRELKDQGP PPSFLELMKV IREEEEEEAS FENESIEEPE ERDGYGRWNH EGDD

Target Information

In patients with cancer, symptoms of limbic and brain-stem dysfunction may result from a paraneoplastic disorder. Two proteins, Ma1 and Ma2, were discovered by presence of autoantibodies against them.
Antibodies to Ma1 and Ma2 proteins identify a paraneoplastic disorder that affects the limbic system, brain stem, and cerebellum.
These autoantibodies were used to clone Ma2, which codes for a protein recognized by serum from 10 patients, but not by serum from 344 control subjects.
Ma2 is selectively expressed by normal brain tissue and by testicular tumors of the patients.
Ma2 shares homology with Ma1, a “brain-testis-cancer” gene related to other paraneoplastic syndromes and tumors.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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