Thermo Fisher Scientific CSPG5 Monoclonal Antibody (4G6)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

ELISA (ELISA)

0.03 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

4G6

Immunogen

CSPG5 (NP_006565, 445 a.a. approximately 539 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CSPG5,uniProtId:O95196-1,ncbiNodeId:9606,antigenRange:445-539,antigenLength:566,antigenImageFileName:H00010675-M02_CSPG5_O95196-1_House_mouse.svg,antigenImageFileNamePDP:H00010675-M02_CSPG5_O95196-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: KKLYLLKTEN TKLRRTNKFR TPSELHNDNF SLSTIAEGSH PNDDPSAPHK IQEVLKSCLK EEESFNIQNS MSPKLEGGKG DQADLDVNCL QNNLT

Target Information

Neuroglycan C is a transmembrane chondroitin sulfate proteoglycan that is exclusively expressed in the central nervous system. NGC gene expression is developmentally regulated being altered by addiction to psychostimulants and by nerve lesion. Its core protein has a particular multidomain structure differing from those of other known proteoglycans, and this protein is modified post-translationally in various ways such as phosphorylation and glycosylation. Neuroglycan C is a novel part-time proteoglycan that changes its structure from a proteoglycan form to a non-proteoglycan form without chondroitin sulfate chains during the development of the cerebellum and retina. Evidence suggests that Neuroglycan C is involved in neuronal circuit formation in the central nervous system.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.