Thermo Fisher Scientific Periplakin Polyclonal Antibody
Periplakin 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Human, Mouse, Rat 시료에서 반응합니다. Western blot과 Immunocytochemistry에 적합하며, 항원 친화 크로마토그래피로 정제된 고순도 제품입니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- Publications: References
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human PPL (Periplakin, UniProt ID: O60437-1, Antigen range: 1–1756) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720800 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
Periplakin is a component of desmosomes and the epidermal cornified envelope in keratinocytes.
- The N-terminal domain interacts with the plasma membrane.
- The C-terminal domain interacts with intermediate filaments.
- Forms complexes with envoplakin via its rod domain.
- May link the cornified envelope, desmosomes, and intermediate filaments.
- AKT1/PKB interacts with Periplakin, suggesting a role as a localization signal in AKT1-mediated signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(PA5-77073_Periplakin_O60437-1_Rabbit.svg 및 PA5-77073_Periplakin_O60437-1_Rabbit_PDP.jpeg)
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