Thermo Fisher Scientific AMPK beta-2 Polyclonal Antibody
AMPK beta-2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 면역세포화학 실험에 적합합니다. 인간, 생쥐, 랫트 반응성이 있으며 항원 친화 크로마토그래피로 정제되었습니다. 고순도(>95%) 제품으로 연구용에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human AMPK beta-2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720802 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
AMPK Beta 2 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit and non-catalytic beta and gamma subunits. It acts as an energy-sensing enzyme that monitors cellular energy status. Upon activation under metabolic stress, AMPK phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and HMG-CoA reductase (HMGCR), key enzymes in fatty acid and cholesterol biosynthesis. AMPK Beta 2 may positively regulate AMPK activity and influence enzyme activity and localization through myristoylation and phosphorylation. It may also serve as an adaptor molecule mediating AMPK complex association.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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