Thermo Fisher Scientific MMP11 Polyclonal Antibody
MMP11 단백질을 인식하는 토끼 유래 폴리클로날 항체로, Western blot, IHC, ICC/IF 등 다양한 응용에 적합합니다. 인간, 마우스, 랫에서 반응하며, 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 보장합니다.
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Thermo Fisher Scientific MMP11 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MMP11 (Accession P24347), corresponding to amino acid residues A68–P118 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818108 |
Product Specific Information
Antibody detects endogenous levels of total MMP11.
Target Information
Stromelysin, a member of the matrix metalloproteinase family, demonstrates wide substrate specificity with the ability to degrade proteoglycan, fibronectin, laminin, casein, and the nonhelical region of collagen.
The stromelysin-3 (MMP-11) gene was originally identified on the basis that it is expressed specifically in stromal cells surrounding invasive breast carcinomas.
MMP-11 is localized by in situ hybridization to the long arm of chromosome 22.
The MMP-11 expression is found more specifically in malignant tumors than in benign ones.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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