Thermo Fisher Scientific Mammaglobin B Polyclonal Antibody
인체 유래 Mammaglobin B 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 사용 가능. 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 유방암 관련 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SCGB2A1 (Accession O75556), corresponding to amino acid residues L3–D53 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818106 |
Product Specific Information
Antibody detects endogenous levels of total Mammaglobin B.
Target Information
Secretoglobins (also called lipophilins or mammaglobins) are small secreted proteins of endocrine-responsive organs and mucosal epithelia that form multimeric complexes and correlate with the development of various human cancers. Lipophilin A and Lipophilin B are orthologs of prostatein (estramustine-binding protein), the major secretory glycoprotein of the rat ventral prostate gland.
Lipophilin A (LIPA, LPHA, SCGB1D1) is a component of a heterodimeric molecule present in human tears. Lipophilin B (LIPB, LPHB, SCGB1D2) mRNA can be overexpressed in breast tumors and shows a high correlation with the mRNA expression profile of mammaglobin.
Histological detection in breast tissue of Mammaglobin A (MGB1, SCGB2A2) and Mammaglobin B (MGB2, LPHC, UGB3, SCGB2A2) is a reliable diagnostic marker for breast tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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