Thermo Fisher Scientific CCRL2 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000–1:3,000

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:100–1:500

Product Specifications

Product Specific Information

Antibody detects endogenous levels of total CCRL2.

Target Information

CCRL2 (C-C chemokine receptor-like 2), also known as chemokine receptor X, human chemokine receptor (HCR), CRAM-A or CRAM-B, is a seven-pass transmembrane protein expressed by monocytes, neutrophils, and dendritic cells in immune tissues such as spleen, fetal liver, bone marrow, and lymph node.
It shares over 40% homology with other C-C chemokine receptors but lacks the conserved DRY motif, which is important for signaling and ligand binding.
C-C chemokine receptors are G-protein coupled, seven-pass transmembrane domain proteins that play a major physiological role in the chemotaxis of T cells and phagocytic cells to sites of inflammation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.