Thermo Fisher Scientific CARD10 Polyclonal Antibody
CARD10 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF 등에 사용 가능. Human 및 Mouse 시료에 반응하며, Affinity chromatography로 정제됨. PBS/glycerol buffer에 보관하며, 연구용으로만 사용.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CARD10 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CARD10 (Accession Q9BWT7), corresponding to amino acid residues T68–Q118 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2852556 |
Product Specific Information
This antibody detects endogenous levels of total CARD10.
Target Information
CARMA proteins belong to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that act as molecular scaffolds facilitating assembly of signal transduction complexes.
CARMA1, CARMA2, and CARMA3 share high sequence and functional homology, but their tissue-specific distribution suggests distinct biological functions.
The CARD domain of CARMA3 interacts with BCL10, a positive regulator of apoptosis and NF-κB activation.
CARMA3 is required for EGF-induced NF-κB activation and contributes to tumor growth in vivo, indicating potential as a therapeutic target in EGFR-driven tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.