Thermo Fisher Scientific Zika Virus NS5 Recombinant Rabbit Monoclonal Antibody (HL2154)
Zika Virus NS5 단백질을 인식하는 Thermo Fisher Scientific의 재조합 Rabbit Monoclonal 항체. Western blot 및 Immunocytochemistry에 사용 가능. HEK293 세포 발현, Protein A 정제, PBS buffer에 보존. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HL2154 |
| Immunogen | Synthetic peptide of Zika virus NS5 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090480 |
Target Information
Zika Virus nonstructural protein 5 (NS5) interacts with the host retinoic acid-inducible gene I (RIG-I), which is an essential signaling molecule for defending pathogen infections. NS5 subsequently represses K63-linked polyubiquitination of RIG-I, attenuates the phosphorylation and nuclear translocation of interferon regulatory factor 3 (IRF3), and inhibits the expression and production of interferon-beta (IFN-beta), thus restricting the RIG-I signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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