Thermo Fisher Scientific CYR61 Recombinant Rabbit Monoclonal Antibody (HL2144)
CYR61 단백질을 인식하는 고특이성 재조합 토끼 단클론 항체. Western blot, IHC, ICC/IF 등 다양한 응용에 적합. Human, Mouse, Rat 반응성. Protein A 정제, 1 mg/mL 농도의 액상 형태. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HL2144 |
| Immunogen | Recombinant fragment of human CYR61 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3094274 |
Target Information
CYR61 is a secreted heparin-binding protein encoded by a growth factor-inducible immediate-early gene that associates with the extracellular matrix and connective tissue. It belongs to the CCN protein family, which includes connective tissue growth factor (CTGF) and the mouse homolog Fisp12. CYR61 functions as an angiogenic inducer by binding to integrin αvβ3, stimulating cell adhesion, migration, and DNA synthesis in human vascular endothelial cells. Expression of CYR61 increases during vessel growth, wound healing, and chondrocyte differentiation, and it is detected in various tumors, where it promotes tumor growth and serves as a marker of tumor progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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