Thermo Fisher Scientific HBEGF Monoclonal Antibody (OTI10B1), TrueMAB
HBEGF 단백질을 인식하는 Mouse IgG2b 단일클론 항체로 Western blot에 최적화됨. 인간 HBEGF(aa 20-208) 재조합 단백질을 면역원으로 제작. 무보존제, 동결건조 형태로 제공되며 -20°C 보관. 연구용으로 EGFR 관련 신호전달 연구에 적합.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10B1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 20–208 of human HBEGF produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
HBEGF is a growth factor that mediates its effects via EGFR, ERBB2, and ERBB4.
It is required for normal cardiac valve formation and heart function, and promotes smooth muscle cell proliferation.
HBEGF may be involved in macrophage-mediated cellular proliferation and is mitogenic for fibroblasts, but not endothelial cells.
It binds EGFR with higher affinity than EGF and acts as a diphtheria toxin receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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