Thermo Fisher Scientific HBEGF Monoclonal Antibody (OTI10A4), TrueMAB
HBEGF 단백질을 인식하는 Mouse monoclonal antibody로 Western blot에 최적화됨. Human 시료 반응성. Lyophilized 형태로 제공되며, PBS 및 trehalose buffer에 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10A4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 20–208 of human HBEGF produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
HBEGF is a growth factor that mediates its effects via EGFR, ERBB2, and ERBB4. It is essential for normal cardiac valve formation and heart function. HBEGF promotes smooth muscle cell proliferation and may be involved in macrophage-mediated proliferation. It is mitogenic for fibroblasts but not endothelial cells, binds EGFR with higher affinity than EGF, and serves as a diphtheria toxin receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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