Thermo Fisher Scientific XPC Polyclonal Antibody
Human 및 Mouse 시료에서 XPC 단백질을 검출하는 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 적합. 두 개의 합성 펩타이드(C/N 말단 유래)를 면역원으로 사용. 액상 형태로 제공되며 -20°C에서 보관. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:10–1:200 | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Two synthetic peptides, individually conjugated to the C-Terminus and N-Terminus respectively of human XPC |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2215321 |
Product Specific Information
- PA3-956 detects XPC in human and mouse cells.
- Suitable for Western blotting and ICC/IF applications.
- Detects a ~125 kDa protein representing XPC.
- Immunogen: two synthetic peptides conjugated to the C- and N-termini of human XPC.
Target Information
The XPC gene encodes a component of the nucleotide excision repair (NER) pathway. This pathway includes multiple components such as Xeroderma pigmentosum (XP) A–G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A.
XPC is crucial in the early steps of global genome NER, particularly in damage recognition, open complex formation, and repair protein complex formation.
Mutations in XPC or other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight and early-onset carcinomas.
Alternatively spliced transcript variants have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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