Thermo Fisher Scientific CD49a Polyclonal Antibody, APC
APC로 결합된 Thermo Fisher Scientific의 CD49a 폴리클로날 항체로, 인간 CD49a(Integrin alpha 1)를 인식합니다. Flow Cytometry에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 낮은 교차 반응성을 보이며, 4°C에서 암소 보관합니다.
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Applications
- Flow Cytometry (Flow): 10 µL per million cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CHO-derived recombinant human Integrin alpha 1/CD49a (Phe29–Pro1141) |
| Conjugate | APC (Allophycocyanin) |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Buffered saline solution with BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE! |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608460 |
Product Specific Information
In direct ELISAs, less than 5% cross-reactivity with recombinant human (rh) Integrin alpha 2, rhIntegrin alpha 11, recombinant mouse (rm) Integrin alpha 2, and rmIntegrin alpha 11 is observed.
Target Information
Integrin alpha 1 (ITGA1) chain associates with the beta 1 (ITGB1) chain to form a heterodimer that functions as a dual laminin/collagen receptor in neural and hematopoietic cells.
ITGA1 has a 206-amino acid I domain in its N-terminal half, followed by three divalent cation-binding sites and a C-terminal transmembrane domain with a short cytoplasmic tail.
It also has 28 potential N-glycosylation sites. Human ITGA1 was expressed in a mouse fibroblast cell line as a 180-kD protein. ITGA1 is involved in early remodeling of osteoarthritic cartilage and plays an essential role in the regulation of mesenchymal stem cell proliferation and cartilage production.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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