Thermo Fisher Scientific SELM Monoclonal Antibody (4C2)
SEL M 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western Blot, ELISA, IP에 사용 가능. 인간 selenoprotein M을 면역원으로 제작. 뇌 조직에서 발현되는 SelM 연구에 적합. 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:2,000 | |
| ELISA (ELISA) | Assay-dependent | |
| Immunoprecipitation (IP) | 1–2 µL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4C2 |
| Immunogen | Purified, recombinant human selenoprotein M protein expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2185101 |
Product Specific Information
A suggested positive control for this product is recombinant human SelM protein.
Target Information
A growing body of evidence relates selenium to cancer prevention, immune system function, male fertility, cardiovascular disorder, control of the aging and neurodiseases process. Selenoproteins are thought to be responsible for the majority of these biomedical effects of selenium. Approximately 17 selenoproteins have been identified until now. Although the function of many selenoproteins are unknown, some play important roles in antioxidant mechanisms. It has been also implicated in the regulation of signaling pathways through catalysis of thiol/disulfide exchange.
Selenoprotein M (SelM) is especially expressed in the mammalian brain and is localized to the perinuclear structures (Golgi/ER). The roles of SelM have not been clearly identified until present time.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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