Thermo Fisher Scientific GPX4 Monoclonal Antibody (7A4)

Applications

Tested Dilution

Publications

ELISA (ELISA)

Assay-dependent

-

Immunoprecipitation (IP)

1-2 µL

-

Product Specifications

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

7A4

Immunogen

Purified, recombinant, human glutathione peroxidase 4 protein expressed in E. coli.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2232543

Product Specific Information

A suggested positive control for this product is HL-60 cells.

Target Information

Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.