Thermo Fisher Scientific GPX4 Monoclonal Antibody (7A4)
Thermo Fisher Scientific의 GPX4 Monoclonal Antibody (7A4)는 인간 Glutathione Peroxidase 4 단백질을 인식하는 Mouse IgG1 항체로, ELISA 및 IP 실험에 적합합니다. HL-60 세포를 양성 대조군으로 권장하며, 세포의 산화 손상 보호 연구에 활용됩니다.
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Applications
ELISA (ELISA)
- Tested Dilution: Assay-dependent
Immunoprecipitation (IP)
- Tested Dilution: 1–2 µL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7A4 |
| Immunogen | Purified, recombinant human glutathione peroxidase 4 protein expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2232543 |
Product Specific Information
A suggested positive control for this product is HL-60 cells.
Target Information
Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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