Thermo Fisher Scientific DPM1 Monoclonal Antibody (5C5A7)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

View 39 publications 39 publications

Immunocytochemistry (ICC/IF)

-

View 2 publications 2 publications

Immunoprecipitation (IP)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Yeast

Published species

Human, Yeast

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

5C5A7

Immunogen

Yeast Dolichol phosphate mannose synthase

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

purified

Storage buffer

HEPES buffered saline

Contains

0.02% sodium azide

Storage conditions

4° C

Shipping conditions

Wet ice

RRID

AB_2536204

Target Information

Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.