Thermo Fisher Scientific TK1 (Thymidine Kinase) Polyclonal Antibody
Fruit fly 유래 TK1 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot 및 IHC(P) 검증 완료. 항원 친화 크로마토그래피로 정제된 고순도 항체. 세포 분열 및 항바이러스 연구에 적합.
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Thermo Fisher Scientific TK1 (Thymidine Kinase) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Fruit fly |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the N-terminus of fruit fly thymidine kinase protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Fruit-fly extract
Target Information
Thymidine Kinase (TK1) is a highly conserved phosphotransferase present in most living cells.
It catalyzes the phosphorylation reaction:
deoxythymidine + ATP → deoxythymidine 5'-phosphate + ADP,
thus participating in the DNA synthesis pathway.
Thymidine kinase is essential for the activity of several antiviral drugs (e.g., AZT) and is used for hybridoma cell line selection in monoclonal antibody production.
Clinically, TK1 serves as a marker for cell proliferation due to its expression during cell division.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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