Thermo Fisher Scientific BCAT1 Polyclonal Antibody
BCAT1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, ICC/IF, ELISA에 사용 가능. Human, Mouse, Rat 반응성. 세포질 내 BCAT1 검출에 적합하며, -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 20–190 of human BCAT1 (NP_005495.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.29 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914013 |
Product Specific Information
- Positive test controls: Jurkat, Raji, SH-SY5Y, Neuro-2a, Mouse brain
- Subcellular localization: Cytoplasm
Immunogen sequence:
EVVGTFKAKD LIVTPATILK EKPDPNNLVF GTVFTDHMLT VEWSSEFGWE KPHIKPLQNL SLHPGSSALH YAVELFEGLK AFRGVDNKIR LFQPNLNMDR MYRSAVRATL PVFDKEELLE CIQQLVKLDQ EWVPYSTSAS LYIRPTFIGT EPSLGVKKPT KALLFVLLSP V
Target Information
This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth.
Two clinical disorders are associated with defects in this enzyme: hypervalinemia and hyperleucine-isoleucinemia.
A mitochondrial form of this enzyme also exists, and mutations in either gene may contribute to these disorders.
Alternatively spliced transcript variants have been described.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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