Thermo Fisher Scientific BCAT1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 20-190 of human BCAT1 (NP_005495.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:BCAT1,uniProtId:P54687-1,ncbiNodeId:9606,antigenRange:20-190,antigenLength:386,antigenImageFileName:PA5-120441_BCAT1_P54687-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120441_BCAT1_P54687-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.29 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914013

Product Specific Information

Positive test controls include: Jurkat, Raji, SH-SY5Y, Neuro-2a, Mouse brain. The target is usually found in the following locations: Cytoplasm.

Immunogen sequence: EVVGTFKAKD LIVTPATILK EKPDPNNLVF GTVFTDHMLT VEWSSEFGWE KPHIKPLQNL SLHPGSSALH YAVELFEGLK AFRGVDNKIR LFQPNLNMDR MYRSAVRATL PVFDKEELLE CIQQLVKLDQ EWVPYSTSAS LYIRPTFIGT EPSLGVKKPT KALLFVLLSP V

Target Information

This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.