Thermo Fisher Scientific SS18 Polyclonal Antibody
Human SS18 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 Immunocytochemistry에 적합. 합성 펩타이드 항원을 이용해 제작되었으며, 액상 형태로 1 mg/mL 농도. PBS, 50% glycerol에 보관하며 -20°C에서 안정적으로 저장 가능.
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- PA599723
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SS18 (Accession Q15532), corresponding to amino acid residues M1–D37 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818656 |
Product Specific Information
Antibody detects endogenous levels of total SYT.
Target Information
The transcriptional coactivator SYT (synovial translocation protein) contains a conserved amino terminal SNH domain and a carboxy terminal QPGY domain, which functions as a transcriptional activating sequence. Synovial sarcoma translocation (SSX) proteins (SSX1–5) are transcriptional repressors containing a repressor domain in their carboxy termini. SSX proteins are localized to the nucleus and expressed in testis and several types of cancers, classifying them as C/T (cancer/testis) antigens. The t(x;18) translocation results in the fusion of the amino terminus of SYT to the carboxy terminus of either SSX1 or SSX2, producing transcriptional activators.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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