Thermo Fisher Scientific MED14 Monoclonal Antibody (483CT11.1.1)
MED14 단백질을 인식하는 Mouse IgM 단일클론 항체로 Western blot에 최적화됨. Human 및 Mouse 시료에 반응하며 비결합형 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능.
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- MA537563
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- pk
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Applications
- Western Blot (WB): Tested dilution 1:500–1:8,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgM |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 483CT11.1.1 |
| Immunogen | Purified His-tagged MED14 protein (fragment) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2897493 |
Target Information
The activation of gene transcription is a multistep process triggered by factors recognizing transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus.
The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1.
It is also a component of other multisubunit complexes, such as thyroid hormone receptor (TR)-associated proteins, which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
This protein contains a bipartite nuclear localization signal and is known to escape chromosome X-inactivation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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