Thermo Fisher Scientific JMJD2C Polyclonal Antibody
JMJD2C/KDM4C 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 Immunoprecipitation에 적합. 1 mg/mL 농도의 액상 비접합 항체로 4°C에서 보관. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 475 and 525 of human Jumonji Domain Containing 2C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
Jumonji domain-containing protein 2C (JMJD2C), also known as Lysine-specific demethylase 4C (KDM4C), is a histone demethylase that specifically demethylates Lys-9 and Lys-36 residues of histone H3, thereby playing a central role in the histone code.
KDM4C does not demethylate histone H3 Lys-4, H3 Lys-27, or H4 Lys-20. It demethylates trimethylated H3 Lys-9 and H3 Lys-36 residues, with no activity on mono- or dimethylated residues.
Demethylation of Lys residues generates formaldehyde and succinate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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