Thermo Fisher Scientific JMJD2C Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2,000-1:10,000

-

Immunoprecipitation (IP)

2-5 µg/mg lysate

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Region between residue 475 and 525 of human Jumonji Domain Containing 2C. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:JMJD2C,uniProtId:Q9H3R0-1,ncbiNodeId:9606,antigenRange:475-525,antigenLength:1056,antigenImageFileName:A300-885A_JMJD2C_Q9H3R0-1_Rabbit.svg,antigenImageFileNamePDP:A300-885A_JMJD2C_Q9H3R0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

tris citrate/phosphate, pH 7-8

Contains

0.09% sodium azide

Storage conditions

4° C

Shipping conditions

Wet ice

Product Specific Information

The recommended shelf life for this product is 1 year from date of receipt.

Target Information

Jumonji domain-containing protein 2C (JMJD2C)/ Lysine-specific demethylase 4C (KDM4C) is a histone demethylase that specifically demethylates Lys-9 and Lys-36 residues of histone H3; thereby, playing a central role in histone code. KDM4C does not demethylate histone H3 Lys-4, H3 Lys-27, or H4 Lys-20. It demethylates trimethylated H3 Lys-9 and H3 Lys-36 residues. There is no activity on mono- or dimethylated residues. Demethylation of Lys residues generates formaldehyde and succinate.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.