Thermo Fisher Scientific Leo1 Polyclonal Antibody
Rabbit polyclonal antibody against human LEO1 protein. Validated for WB, IHC (P), and IP applications. Offers high specificity and sensitivity with broad species reactivity. Supplied as a liquid at 1 mg/mL, stored at 4°C, shipped on wet ice.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:10,000–1:25,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 550 and 600 of human senescence downregulated LEO1-like protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections
- Predicted reactivity (based on 100% sequence identity): Rat and Orangutan
Target Information
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, acting both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme, regulated by specific stimulatory events, and is responsible for prostanoid biosynthesis involved in inflammation and mitogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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