Thermo Fisher Scientific Insulin/IRDN (beta-Cell and Insulinoma Marker) Monoclonal Antibody (rIRDN/4782)
인슐린 및 인슐린종 마커로 사용되는 단클론 항체로, 인간 시료에 반응합니다. IHC(PFA 고정)에서 0.1–0.2 µg/mL 농도로 사용 가능하며, 고순도 Protein A/G 정제 제품입니다. 연구용으로만 사용되며, -20°C에서 보관합니다.
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Thermo Fisher Scientific Insulin/IRDN (beta-Cell and Insulinoma Marker) Monoclonal Antibody (rIRDN/4782)
Applications
- Immunohistochemistry (PFA fixed) (IHC (PFA))
Tested Dilution: 0.1–0.2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | rIRDN/4782 |
| Immunogen | Recombinant full-length human Insulin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein, and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids.
Insulin is a 51-amino acid polypeptide produced from proinsulin, which is post-translationally cleaved into peptide A and peptide B chains linked via disulfide bonds and one C-peptide molecule.
Deficiency of insulin results in diabetes mellitus, a leading cause of morbidity and mortality. Insulin is also found in tumors of β-cell origin such as insulinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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