
Thermo Fisher Scientific TTK Monoclonal Antibody (OTI1D4), TrueMAB
TTK 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI1D4). Western blot에 검증됨. Human 시료에 반응하며, Lyophilized 형태로 제공. PBS buffer에 trehalose 포함, -20°C에서 보관 권장. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 189–464 of human TTK produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
TTK is a serine/threonine kinase closely related to SPK1, PIM1, and CDC2 kinases. It functions as a dual-specificity kinase capable of phosphorylating tyrosine residues. The enzyme consists of a catalytic subunit and a constant regulatory subunit A, which acts as a scaffold for assembly with variable regulatory B subunits. TTK encodes the alpha isoform of the constant regulatory subunit A. Multiple alternatively spliced transcript variants have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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