Thermo Fisher Scientific H3K18cr Recombinant Rabbit Monoclonal Antibody (21H13L11)
H3K18cr 변형을 인식하는 재조합 토끼 단클론 항체로, Western blot과 면역세포화학에 적합합니다. 높은 특이성과 재현성을 제공하며, Protein A로 정제된 액상 형태입니다. 인간 및 마우스 시료에 반응하며, 4°C 또는 -20°C에서 안정적으로 보관 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 21H13L11 |
| Immunogen | Peptide corresponding to human H3.1crK18 [aa14–aa25] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809239 |
Product Specific Information
This antibody is predicted to react with Rat and Bovine.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned, and individual clones are screened to select optimal candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes.
Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of H2A, H2B, H3, and H4.
Chromatin fibers are further compacted through interactions with linker histone H1, forming higher-order chromatin structures.
The H3 gene is intronless, lacks a polyA tail, contains a palindromic termination element, and is located separately from other H3 genes on chromosome 6p22-p21.3.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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