Thermo Fisher Scientific ETV1 Monoclonal Antibody (2A8)
ETV1 단백질을 인식하는 Mouse monoclonal antibody로 Western blot 및 ELISA에 적합. Human 시료에 반응하며, Affinity chromatography로 정제됨. PBS buffer에 보존되며, -20°C에서 보관 권장.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2A8 |
| Immunogen | ETV1 (NP_004947, 148 a.a. approximately 257 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
LHHASPNSTH TPKPDRAFPA HLPPSQSIPD SSYPMDHRFR RQLSEPCNSF PPLPTMPREG RPMYQRQMSE PNIPFPPQGF KQEYHDPVYE HNTMVGSAAS QSFPPPLMIK
Target Information
ETV1 (ets variant gene 1):
Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element. All Ets proteins recognize the same central core sequence but interact with unique flanking sequences.
ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3'. It is highly expressed in brain, testis, lung, and heart, and moderately expressed in spleen, pancreas, colon, and small intestine. During development, ER81 displays unique expression patterns suggesting a role in organogenesis.
ERK-1 activates ER81 transcriptional activity, while MAPKAP kinase 2 inhibits it.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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