Thermo Fisher Scientific ETV1 Monoclonal Antibody (2A8)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

ELISA (ELISA)

1 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

2A8

Immunogen

ETV1 (NP_004947, 148 a.a. approximately 257 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ETV1,uniProtId:P50549-1,ncbiNodeId:9606,antigenRange:148-257,antigenLength:477,antigenImageFileName:H00002115-M01_ETV1_P50549-1_House_mouse.svg,antigenImageFileNamePDP:H00002115-M01_ETV1_P50549-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: LHHASPNSTH TPKPDRAFPA HLPPSQSIPD SSYPMDHRFR RQLSEPCNSF PPLPTMPREG RPMYQRQMSE PNIPFPPQGF KQEYHDPVYE HNTMVGSAAS QSFPPPLMIK

Target Information

ETV1: ets variant gene 1. Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5-GGAA-3 element. All of the Ets proteins recognize the same central core sequence but each protein interacts with unique sequences that flank this core. ER81 (also designated ETV1) binds the motif 5-CGGAA/T-3. ER81 is highly expressed in brain, testis, lung and heart. ER81 is also moderately expressed in spleen, pancreas, colon and small intestine. During development, ER81 displays a unique expression patterns which suggests that this transcriptional factor might play an important role in organogenesis. ERK-1 activates ER81 transcriptional activity while MAPKAP kinase 2 inhibits ER81.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.