Thermo Fisher Scientific ETV1 Monoclonal Antibody (4C12)
ETV1 단백질을 인식하는 Mouse IgG1 단클론 항체. Western blot과 ELISA에 적합하며 높은 특이성과 재현성을 제공. 연구용으로 인간 ETV1 발현 분석에 활용 가능. 액상 형태로 -20°C에서 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.1 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4C12 |
| Immunogen | ETV1 (NP_004947, 148–257 a.a) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
LHHASPNSTH TPKPDRAFPA HLPPSQSIPD SSYPMDHRFR RQLSEPCNSF PPLPTMPREG RPMYQRQMSE PNIPFPPQGF KQEYHDPVYE HNTMVGSAAS QSFPPPLMIK
Target Information
ETV1 (ets variant gene 1):
Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element. All Ets proteins recognize the same central core sequence but interact with unique flanking sequences.
ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3'. ER81 is highly expressed in brain, testis, lung, and heart, and moderately expressed in spleen, pancreas, colon, and small intestine. During development, ER81 shows unique expression patterns suggesting a role in organogenesis. ERK-1 activates ER81 transcriptional activity, while MAPKAP kinase 2 inhibits it.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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