Thermo Fisher Scientific Human LKB1 Synthetic Peptide
인간 LKB1 단백질의 C-말단 15개 아미노산 서열에 해당하는 합성 펩타이드로, PA5-20325 항체의 블로킹 펩타이드로 사용 가능. 순도 높은 액상 형태로 제공되며, PBS 버퍼(pH 7.2)에 0.1% BSA와 0.02% sodium azide 포함. 연구용으로만 사용.
- 카탈로그번호
- PEP0445
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human LKB1 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids near the carboxy terminus of human LKB1.
PEP-0445 can be used as a blocking peptide with polyclonal antibody PA5-20325.
Target Information
LKB1 (also known as STK11 - Serine/threonine-protein kinase STK11) is a tumor suppressor and a member of the serine/threonine kinase family.
It physically associates with p53 and regulates specific p53-dependent apoptosis pathways.
LKB1 is present in both the cytoplasm and nucleus and translocates to mitochondria during apoptosis.
It acts as a master upstream kinase regulating AMPK and AMPK-related kinases.
Mutations in the LKB1 gene are associated with Peutz-Jeghers syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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