Thermo Fisher Scientific Human RPAIN Synthetic Peptide
Human RPAIN 단백질의 C-말단 17개 아미노산 서열을 기반으로 한 합성 펩타이드. RPA 상호작용 단백질 연구용으로 사용. PA5-20326 항체의 블로킹 펩타이드로 적합. 고순도 정제, 액상 형태로 제공.
- 카탈로그번호
- PEP0446
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human RPAIN Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the carboxy terminus of human RPA interacting protein.
PEP-0446 can be used as a blocking peptide with polyclonal antibody PA5-20326.
Target Information
Replication protein A (RPA) is a single-stranded-DNA binding protein involved in numerous eukaryotic DNA processes including replication, repair, and recombination.
RPA interacting protein (RPA IP) acts as an adapter protein involved in RPA nuclear import, distinct from typical importin-mediated nuclear transport.
Multiple isoforms of RPA IP exist:
- The longest isoform localizes to the cytoplasm.
- Isoform 2 is sumoylated and located in the PML nuclear body within the nucleus.
It has been suggested that this isoform mediates localization of the RPA complex into the PML nuclear body, participating in RPA function in DNA metabolism.
Usage Notes
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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